Edward Mocarski
- Department of Microbiology and Immunology
Professor Emeritus
- (404) 727-9442
- mocarski@emory.edu
-
Emory University School of Medicine
Microbiology and Immunology
1462 Clifton Rd., Room 429
Overview
Edward S. Mocarski, Jr. received an A.B. from Rutgers University in 1974 and a Ph.D. from the University of Iowa in 1979, both degrees in microbiology. He completed a postdoctoral fellowship in virology at The University of Chicago with Dr. Bernard Roizman in 1982. Dr. Mocarski joined Stanford University in 1983 and was Chairman of the Department of Microbiology and Immunology and Professor of Microbiology and Immunology at Stanford University School of Medicine as well as Associate Dean of Research within Stanford Universitys Provosts Office. He retired from Stanford and became Professor Emeritus when he joined the faculty at Emory University School of Medicine in 2006 as Robert W. Woodruff Professor in the Department of Microbiology and Immunology and the Emory Vaccine Center. He was Distinguished Fellow at MedImmune, LLC, where he managed an expansion of vaccine pipeline research with particular attention to herpes viruses, including cytomegalovirus. He returned to Emory as a full-time faculty member in 2011.
Research
Dr. Mocarskis research focuses on all aspects of the biology and pathogenesis of cytomegalovirus (CMV), an opportunistic herpesvirus; in particular, on integrating biochemical, molecular, cellular and intact animal approaches to investigate the biological properties of this virus and its close relatives. He has made key contributions to the identification of replication functions, latent reservoir in myelomonocytic progenitors, immunomodulatory functions, and cellular response to viral infection. His research has opened dramatic new understanding of cell death pathways in host defense and development. He is an internationally recognized leader in research on CMV and broadly knowledgeable in the area of herpesviruses and host control of viral infection. Dr. Mocarski has received many honors. He serves on the editorial boards of Virology, Journal of Biological Chemistry and Journal of Virology, and is a manuscript reviewer for numerous prominent journals. He has been a member on many national and international panels. He has served on international organizing committees of major conferences and herpesvirus workshops. He is the author and coauthor of more than 140 peer-reviewed articles; other publications include review articles and book chapters; and he is coauthor and editor of the major textbook, Human Herpesviruses: Biology, Therapy and Immunoprophylaxis (Cambridge Press, Cambridge, 2007), now accessible through PubMed.
Academic Appointment
- Professor Emeritus, Stanford University School of Medicine
- Robert W. Woodruff Professor of Microbiology & Immunology, Emory University
Education
Degrees
- PhD from University of Iowa
- A.B. from Rutgers University
Research
Publications
-
Perspective on the 65-Year Anniversary of the Discovery of Cytomegalovirus.
Viruses Volume: 17
01/09/2025 Authors: Mocarski ES -
Cytomegalovirus Biology Viewed Through a Cell Death Suppression Lens.
Viruses Volume: 16
11/23/2024 Authors: Mocarski ES -
The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas.
PLoS Pathog Volume: 19 Page(s): e1011387
05/01/2023 Authors: Cleverley TL; Peddineni S; Guarner J; Cingolani F; Garcia PK; Koehler H; Mocarski ES; Kalman D -
Encephalitis and poor neuronal death-mediated control of herpes simplex virus in human inherited RIPK3 deficiency.
Sci Immunol Volume: 8 Page(s): eade2860
04/21/2023 Authors: Liu Z; Garcia Reino EJ; Harschnitz O; Guo H; Chan Y-H; Khobrekar NV; Hasek ML; Dobbs K; Rinchai D; Materna M -
A microbiota and dietary metabolite integrates DNA repair and cell death to regulate embryo viability and aneuploidy during aging.
Sci Adv Volume: 9 Page(s): eade8653
02/24/2023 Authors: Sonowal R; Swimm AI; Cingolani F; Parulekar N; Cleverley TL; Sahoo A; Ranawade A; Chaudhuri D; Mocarski ES; Koehler H -
The RIPK3 Scaffold Regulates Lung Inflammation During Pseudomonas Aeruginosa Pneumonia.
Am J Respir Cell Mol Biol Volume: 68 Page(s): 150 - 160
02/01/2023 Authors: Lyons JD; Mandal P; Otani S; Chihade DB; Easley KF; Swift DA; Burd EM; Liang Z; Koval M; Mocarski ES -
Programmed Necrosis in Host Defense.
Curr Top Microbiol Immunol Volume: 442 Page(s): 1 - 40
01/01/2023 Authors: Mocarski ES -
p38MAPK guards the integrity of endosomal compartments through regulating necrotic death.
Sci Rep Volume: 12 Page(s): 16357
09/29/2022 Authors: Yao J; Atasheva S; Toy R; Blanchard EL; Santangelo PJ; Roy K; Mocarski ES; Shayakhmetov DM -
KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine.
NPJ Vaccines Volume: 7 Page(s): 108
09/20/2022 Authors: Casper C; Corey L; Cohen JI; Damania B; Gershon AA; Kaslow DC; Krug LT; Martin J; Mbulaiteye SM; Mocarski ES -
RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis.
PLoS Pathog Volume: 18 Page(s): e1010857
09/01/2022 Authors: Guo H; Koehler HS; Mocarski ES; Dix RD -
Programmed Cell Death-Dependent Host Defense in Ocular Herpes Simplex Virus Infection.
Front Microbiol Volume: 13 Page(s): 869064
01/01/2022 Authors: Guo H; Koehler HS; Dix RD; Mocarski ES -
Viral Z-RNA triggers ZBP1-dependent cell death.
Curr Opin Virol Volume: 51 Page(s): 134 - 140
12/01/2021 Authors: Balachandran S; Mocarski ES -
Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness.
Viruses Volume: 13
08/27/2021 Authors: Mandal P; Nagrani LN; Hernandez L; McCormick AL; Dillon CP; Koehler HS; Roback L; Alnemri ES; Green DR; Mocarski ES -
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis.
Cell Host Microbe Volume: 29 Page(s): 1266 - 1276.e5
08/11/2021 Authors: Koehler H; Cotsmire S; Zhang T; Balachandran S; Upton JW; Langland J; Kalman D; Jacobs BL; Mocarski ES -
TNF-dependent hyperactivation of RIPK1-dependent cytotoxic signaling during embryogenesis and inflammation.
PLoS Biol Volume: 19 Page(s): e3001371
08/01/2021 Authors: Mocarski ES; Mandal P -
Concern over use of the term Z-DNA.
Nature Volume: 594 Page(s): 333
06/01/2021 Authors: Herbert A; Wang AH-J; Jovin TM; Mocarski ES; Pasparakis M; Vasquez KM -
Integrated evaluation of lung disease in single animals.
PLoS One Volume: 16 Page(s): e0246270
01/01/2021 Authors: Mandal P; Lyons JD; Burd EM; Koval M; Mocarski ES; Coopersmith CM -
TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis.
Viruses Volume: 12
10/28/2020 Authors: Mandal P; McCormick AL; Mocarski ES -
Recognizing limits of Z-nucleic acid binding protein (ZBP1/DAI/DLM1) function.
FEBS J Volume: 287 Page(s): 4362 - 4369
10/01/2020 Authors: Koehler HS; Feng Y; Mandal P; Mocarski ES -
Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 20109 - 20116
08/18/2020 Authors: Lane RK; Guo H; Fisher AD; Diep J; Lai Z; Chen Y; Upton JW; Carette J; Mocarski ES; Kaiser WJ -
Correction for Chaudhry et al., Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 19606
08/11/2020 -
Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 12961 - 12968
06/09/2020 Authors: Chaudhry MZ; Casalegno-Garduno R; Sitnik KM; Kasmapour B; Pulm A-K; Brizic I; Eiz-Vesper B; Moosmann A; Jonjic S; Mocarski ES -
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
Elife Volume: 9
06/09/2020 Authors: Kim EH; Woodruff MC; Grigoryan L; Maier B; Lee SH; Mandal P; Cortese M; Natrajan MS; Ravindran R; Ma H -
Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts.
Genome Biol Volume: 21 Page(s): 80
03/26/2020 Authors: Mullin BH; Tickner J; Zhu K; Kenny J; Mullin S; Brown SJ; Dudbridge F; Pavlos NJ; Mocarski ES; Walsh JP -
Prorapeutic vaccination against shared antigens induced in future tumors.
Volume: 8 Page(s): 98 - 99
03/01/2020 Authors: Garrido G; Schrand B; Levay A; Rabasa A; Ferrantella A; Da Silva D; D'Eramo F; Marijt K; Daley-Bauer L; Kwon D -
HIF1 Regulates Early Metabolic Changes due to Activation of Innate Immunity in Nuclear Reprogramming.
Stem Cell Reports Volume: 14 Page(s): 192 - 200
02/11/2020 Authors: Liu C; Ruan H; Himmati F; Zhao M-T; Chen CC; Makar M; Chen IY; Sallam K; Mocarski ES; Sayed D -
Human Cytomegalovirus (Herpesviridae)
Encyclopedia of Virology: Volume 1-5, Fourth Edition Volume: 1-5 Page(s): 441 - 459
01/01/2020 Authors: Mocarski ES -
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA.
Cell Host Microbe Volume: 26 Page(s): 564
10/09/2019 Authors: Upton JW; Kaiser WJ; Mocarski ES -
Caspase-8-dependent control of NK- and T cell responses during cytomegalovirus infection.
Med Microbiol Immunol Volume: 208 Page(s): 555 - 571
08/01/2019 Authors: Feng Y; Daley-Bauer LP; Mocarski ES -
Caspase-8 restricts natural killer cell accumulation during MCMV Infection.
Med Microbiol Immunol Volume: 208 Page(s): 543 - 554
08/01/2019 Authors: Feng Y; Daley-Bauer LP; Roback L; Potempa M; Lanier LL; Mocarski ES -
Caspase-8 restricts antiviral CD8 T cell hyperaccumulation.
Proc Natl Acad Sci U S A Volume: 116 Page(s): 15170 - 15177
07/23/2019 Authors: Feng Y; Daley-Bauer LP; Roback L; Guo H; Koehler HS; Potempa M; Lanier LL; Mocarski ES -
Loss of Necroptosis and Apoptosis Allows Increased Virus Spread Following Corneal Infection with Herpes Simplex Virus Type 1 (HSV-1)
Volume: 60
07/01/2019 Authors: Guo H; Feng Y; Daley-Bauer L; Dix RD; Mocarski E -
RIPK3 NON-KINASE FUNCTION ACTIVATES NFKB TO DRIVE CYTOKINE PRODUCTION AND MORTALITY FOLLOWING PSEUDOMONAS AERUGINOSA PNEUMONIA
Volume: 51 Page(s): 148 - 149
06/01/2019 Authors: Lyons J; Mandal P; Chihade D; Koehler H; Otani S; Burd E; Liang Z; Mocarski E; Coopersmith C -
Herpes simplex virus 1 ICP6 impedes TNF receptor 1-induced necrosome assembly during compartmentalization to detergent-resistant membrane vesicles.
J Biol Chem Volume: 294 Page(s): 991 - 1004
01/18/2019 Authors: Ali M; Roback L; Mocarski ES -
Remarkably Robust Antiviral Immune Response despite Combined Deficiency in Caspase-8 and RIPK3.
J Immunol Volume: 201 Page(s): 2244 - 2255
10/15/2018 Authors: Feng Y; Livingston-Rosanoff D; Roback L; Sundararajan A; Speck SH; Mocarski ES; Daley-Bauer LP -
Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1.
Cell Death Dis Volume: 9 Page(s): 816
07/26/2018 Authors: Guo H; Gilley RP; Fisher A; Lane R; Landsteiner VJ; Ragan KB; Dovey CM; Carette JE; Upton JW; Mocarski ES -
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Immunity Volume: 49 Page(s): 42 - 55.e6
07/17/2018 Authors: Mandal P; Feng Y; Lyons JD; Berger SB; Otani S; DeLaney A; Tharp GK; Maner-Smith K; Burd EM; Schaeffer M -
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Mol Cell Volume: 70 Page(s): 936 - 948.e7
06/07/2018 Authors: Dovey CM; Diep J; Clarke BP; Hale AT; McNamara DE; Guo H; Brown NW; Cao JY; Grace CR; Gough PJ -
Proteasome inhibition blocks necroptosis by attenuating death complex aggregation.
Cell Death Dis Volume: 9 Page(s): 346
03/01/2018 Authors: Ali M; Mocarski ES -
Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3.
Proc Natl Acad Sci U S A Volume: 114 Page(s): 11506 - 11511
10/24/2017 Authors: Koehler H; Cotsmire S; Langland J; Kibler KV; Kalman D; Upton JW; Mocarski ES; Jacobs BL -
Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo.
Virus Genes Volume: 53 Page(s): 650 - 655
08/01/2017 Authors: Surez NM; Lau B; Kemble GM; Lee R; Mocarski ES; Wilkinson GWG; Adler SP; McVoy MA; Davison AJ -
Retinoic Acid Inducible Gene 1 Protein (RIG1)-Like Receptor Pathway Is Required for Efficient Nuclear Reprogramming.
Stem Cells Volume: 35 Page(s): 1197 - 1207
05/01/2017 Authors: Sayed N; Ospino F; Himmati F; Lee J; Chanda P; Mocarski ES; Cooke JP -
Mouse cytomegalovirus M36 and M45 death suppressors cooperate to prevent inflammation resulting from antiviral programmed cell death pathways.
Proc Natl Acad Sci U S A Volume: 114 Page(s): E2786 - E2795
03/28/2017 Authors: Daley-Bauer LP; Roback L; Crosby LN; McCormick AL; Feng Y; Kaiser WJ; Mocarski ES -
A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men.
J Infect Dis Volume: 214 Page(s): 1341 - 1348
11/01/2016 Authors: Adler SP; Manganello A-M; Lee R; McVoy MA; Nixon DE; Plotkin S; Mocarski E; Cox JH; Fast PE; Nesterenko PA -
RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Cell Host Microbe Volume: 20 Page(s): 13 - 24
07/13/2016 Authors: Nogusa S; Thapa RJ; Dillon CP; Liedmann S; Oguin TH; Ingram JP; Rodriguez DA; Kosoff R; Sharma S; Sturm O -
RIP3 MEDIATES INFLAMMATION AND MORTALITY IN PSEUDOMONAS AERUGINOSA PNEUMONIA
Volume: 45 Page(s): 39 - 40
06/01/2016 Authors: Lyons JD; Mandel P; Chen C; Klingensmith N; Kaiser WJ; Mocarski E; Coopersmith C -
T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.
Nat Immunol Volume: 17 Page(s): 583 - 592
05/01/2016 Authors: Martin BN; Wang C; Zhang C-J; Kang Z; Gulen MF; Zepp JA; Zhao J; Bian G; Do J-S; Min B -
Environmental cues in Casp8-deficient mice enhance virus-specific T cell expansion and terminal differentiation
Volume: 196
05/01/2016 Authors: Feng Y; Daley-Bauer L; Roback L; Mocarski E -
Identifying Fas/CD95 non-apoptotic signaling pathways associated with T cell differentiation
Volume: 196
05/01/2016 Authors: Thomas SK; Ouyang C; Cruz AC; Klebanoff CA; Yamamoto TN; Chan FK; Mocarski ES; Roback L; Restifo NP; Siegei RM -
CASPASE 8 AND RIP3 ARE NOT REQUIRED FOR NUCLEAR REPROGRAMMING AND DIFFERENTIATION
Volume: 64 Page(s): 634 - 634
02/01/2016 Authors: Wu D; Sayed N; Huang C; Cooke JP; Mocarski E -
Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
J Biol Chem Volume: 290 Page(s): 20167 - 20184
08/14/2015 Authors: Antonopoulos C; Russo HM; El Sanadi C; Martin BN; Li X; Kaiser WJ; Mocarski ES; Dubyak GR -
Stanley Plotkin: the bright spark of cytomegalovirus vaccines
Medical Microbiology and Immunology Volume: 204 Page(s): 243 - 245
06/27/2015 Authors: Mocarski ES -
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Nat Commun Volume: 6 Page(s): 7515
06/24/2015 Authors: Kang S; Fernandes-Alnemri T; Rogers C; Mayes L; Wang Y; Dillon C; Roback L; Kaiser W; Oberst A; Sagara J -
Stanley Plotkin: the bright spark of cytomegalovirus vaccines.
Med Microbiol Immunol Volume: 204 Page(s): 243 - 245
06/01/2015 Authors: Mocarski ES -
Manipulation of apoptosis and necroptosis signaling by herpesviruses.
Med Microbiol Immunol Volume: 204 Page(s): 439 - 448
06/01/2015 Authors: Guo H; Kaiser WJ; Mocarski ES -
Balancing Innate Immunity Activation and Death Signals for Vascular Regeneration
VASCULAR MEDICINE Volume: 20 Page(s): 277 - 278
06/01/2015 Authors: Ospino F; Chanda P; Cooke J; Wu D; Kaiser W; Mocarski ES; Sayed N -
Suppression of RIP3-dependent necroptosis by human cytomegalovirus.
J Biol Chem Volume: 290 Page(s): 11635 - 11648
05/01/2015 Authors: Omoto S; Guo H; Talekar GR; Roback L; Kaiser WJ; Mocarski ES -
Necroptosis: The Trojan horse in cell autonomous antiviral host defense.
Virology Volume: 479-480 Page(s): 160 - 166
05/01/2015 Authors: Mocarski ES; Guo H; Kaiser WJ -
Necroptosis: The Trojan horse in cell autonomous antiviral host defense
Virology Volume: 479-480 Page(s): 160 - 166
05/01/2015 Authors: Mocarski ES; Guo H; Kaiser WJ -
The immunological underpinnings of vaccinations to prevent cytomegalovirus disease.
Cell Mol Immunol Volume: 12 Page(s): 170 - 179
03/01/2015 Authors: McCormick AL; Mocarski ES -
The A, B, Cs of herpesvirus capsids.
Viruses Volume: 7 Page(s): 899 - 914
02/26/2015 Authors: Tandon R; Mocarski ES; Conway JF -
Herpes simplex virus suppresses necroptosis in human cells.
Cell Host Microbe Volume: 17 Page(s): 243 - 251
02/11/2015 Authors: Guo H; Omoto S; Harris PA; Finger JN; Bertin J; Gough PJ; Kaiser WJ; Mocarski ES -
MicroRNA miR-21 attenuates human cytomegalovirus replication in neural cells by targeting Cdc25a.
J Virol Volume: 89 Page(s): 1070 - 1082
01/15/2015 Authors: Fu Y-R; Liu X-J; Li X-J; Shen Z-Z; Yang B; Wu C-C; Li J-F; Miao L-F; Ye H-Q; Qiao G-H -
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.
Elife Volume: 3
12/02/2014 Authors: Rickard JA; Anderton H; Etemadi N; Nachbur U; Darding M; Peltzer N; Lalaoui N; Lawlor KE; Vanyai H; Hall C -
RIP3 induces apoptosis independent of pronecrotic kinase activity.
Mol Cell Volume: 56 Page(s): 481 - 495
11/20/2014 Authors: Mandal P; Berger SB; Pillay S; Moriwaki K; Huang C; Guo H; Lich JD; Finger J; Kasparcova V; Votta B -
Cytomegaloviruses
Fields Virology Volume: 1 Page(s): 1960 - 2014
11/03/2014 Authors: Mocarski ES; Shenk T; Griffiths PD; Pass RF -
Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1 production in response to -glucans and the fungal pathogen, Candida albicans.
J Immunol Volume: 193 Page(s): 2519 - 2530
09/01/2014 Authors: Ganesan S; Rathinam VAK; Bossaller L; Army K; Kaiser WJ; Mocarski ES; Dillon CP; Green DR; Mayadas TN; Levitz SM -
Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma.
Endocr Pathol Volume: 25 Page(s): 321 - 323
09/01/2014 Authors: Al-Bazzaz S; Karamchandani J; Mocarski E; Horvath E; Rotondo F; Kovacs K -
Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.
J Immunol Volume: 192 Page(s): 5476 - 5480
06/15/2014 Authors: Berger SB; Kasparcova V; Hoffman S; Swift B; Dare L; Schaeffer M; Capriotti C; Cook M; Finger J; Hughes-Earle A -
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.
Proc Natl Acad Sci U S A Volume: 111 Page(s): 7753 - 7758
05/27/2014 Authors: Kaiser WJ; Daley-Bauer LP; Thapa RJ; Mandal P; Berger SB; Huang C; Sundararajan A; Guo H; Roback L; Speck SH -
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Proc Natl Acad Sci U S A Volume: 111 Page(s): 7391 - 7396
05/20/2014 Authors: Weng D; Marty-Roix R; Ganesan S; Proulx MK; Vladimer GI; Kaiser WJ; Mocarski ES; Pouliot K; Chan FK-M; Kelliher MA -
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
Proceedings of the National Academy of Sciences of the United States of America Volume: 111 Page(s): 7391 - 7396
05/20/2014 Authors: Weng D; Marty-Roix R; Ganesan S; Proulx MK; Vladimer GI; Kaiser WJ; Mocarski ES; Pouliot K; Chan FKM; Kelliher MA -
Highly acidic C-terminal region of cytomegalovirus pUL96 determines its functions during virus maturation independently of a direct pp150 interaction.
J Virol Volume: 88 Page(s): 4493 - 4503
04/01/2014 Authors: Brechtel TM; Mocarski ES; Tandon R -
Cytomegalovirus hijacks CX3CR1(hi) patrolling monocytes as immune-privileged vehicles for dissemination in mice.
Cell Host Microbe Volume: 15 Page(s): 351 - 362
03/12/2014 Authors: Daley-Bauer LP; Roback LJ; Wynn GM; Mocarski ES -
True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity.
J Immunol Volume: 192 Page(s): 2019 - 2026
03/01/2014 Authors: Mocarski ES; Kaiser WJ; Livingston-Rosanoff D; Upton JW; Daley-Bauer LP -
Natural antisense transcripts of UL123 packaged in human cytomegalovirus virions.
Arch Virol Volume: 159 Page(s): 147 - 151
01/01/2014 Authors: Yang C-Q; Miao L-F; Pan X; Wu C-C; Rayner S; Mocarski ES; Ye H-Q; Luo M-H -
Transcription of true late (2) cytomegalovirus genes requires UL92 function that is conserved among beta- and gammaherpesviruses.
J Virol Volume: 88 Page(s): 120 - 130
01/01/2014 Authors: Omoto S; Mocarski ES -
Priorities for CMV vaccine development.
Vaccine Volume: 32 Page(s): 4 - 10
12/17/2013 Authors: Krause PR; Bialek SR; Boppana SB; Griffiths PD; Laughlin CA; Ljungman P; Mocarski ES; Pass RF; Read JS; Schleiss MR -
Apaf1 apoptotic function critically limits Sonic hedgehog signaling during craniofacial development.
Cell Death Differ Volume: 20 Page(s): 1510 - 1520
11/01/2013 Authors: Long AB; Kaiser WJ; Mocarski ES; Caspary T -
Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1 via caspase-8 in dendritic cells.
J Immunol Volume: 191 Page(s): 4789 - 4803
11/01/2013 Authors: Antonopoulos C; El Sanadi C; Kaiser WJ; Mocarski ES; Dubyak GR -
Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.
J Biol Chem Volume: 288 Page(s): 31268 - 31279
10/25/2013 Authors: Kaiser WJ; Sridharan H; Huang C; Mandal P; Upton JW; Gough PJ; Sehon CA; Marquis RW; Bertin J; Mocarski ES -
Caspase-8 regulates beta-glucan induced IL-1 beta production and cell death
Volume: 63 Page(s): 263 - 264
09/01/2013 Authors: Ganesan S; Rathinam VAK; Bossaller L; Kaiser WJ; Mocarski ES; Green DR; Silverman NS; Fitzgerald KA -
Cytomegalovirus UL91 is essential for transcription of viral true late (2) genes.
J Virol Volume: 87 Page(s): 8651 - 8664
08/01/2013 Authors: Omoto S; Mocarski ES -
Viral modulation of programmed necrosis.
Curr Opin Virol Volume: 3 Page(s): 296 - 306
06/01/2013 Authors: Kaiser WJ; Upton JW; Mocarski ES -
Cytomegaloviruses
Fields Virology: Sixth Edition Volume: 1
05/21/2013 Authors: Mocarski ES; Shenk T; Griffiths PD; Pass RF -
Remarkably intact antiviral CD8 T cell response despite the absence of caspase 8 apoptotic and RIP3 necrotic pathways
Volume: 190
05/01/2013 Authors: Livingston-Rosanoff D; Daley-Bauer L; Mocarski E -
Desirability and feasibility of a vaccine against cytomegalovirus.
Vaccine Volume: 31 Suppl 2 Page(s): B197 - B203
04/18/2013 Authors: Griffiths P; Plotkin S; Mocarski E; Pass R; Schleiss M; Krause P; Bialek S -
The need and challenges for development of an Epstein-Barr virus vaccine.
Vaccine Volume: 31 Suppl 2 Page(s): B194 - B196
04/18/2013 Authors: Cohen JI; Mocarski ES; Raab-Traub N; Corey L; Nabel GJ -
Gene products of the embedded m41/m41.1 locus of murine cytomegalovirus differentially influence replication and pathogenesis.
Virology Volume: 436 Page(s): 274 - 283
02/20/2013 Authors: Crosby LN; McCormick AL; Mocarski ES -
Multiplicity-dependent activation of a serine protease-dependent cytomegalovirus-associated programmed cell death pathway.
Virology Volume: 435 Page(s): 250 - 257
01/20/2013 Authors: McCormick AL; Roback L; Wynn G; Mocarski ES -
Myeloid Cell Recruitment and Function in Cytomegalovirus Dissemination and Immunity
Page(s): 363 - 373
01/01/2013 Authors: Daley-Bauer LP; Mocarski ES -
Cell Death Pathways Controlled by Cytomegaloviruses
CYTOMEGALOVIRUSES: FROM MOLECULAR PATHOGENESIS TO INTERVENTION, VOL I Page(s): 264 - 277
01/01/2013 Authors: McCormick AL; Mocarski ES -
Cutting edge: FAS (CD95) mediates noncanonical IL-1 and IL-18 maturation via caspase-8 in an RIP3-independent manner.
J Immunol Volume: 189 Page(s): 5508 - 5512
12/15/2012 Authors: Bossaller L; Chiang P-I; Schmidt-Lauber C; Ganesan S; Kaiser WJ; Rathinam VAK; Mocarski ES; Subramanian D; Green DR; Silverman N -
Antiviral T cell response triggers cytomegalovirus hepatitis in mice.
J Virol Volume: 86 Page(s): 12879 - 12890
12/01/2012 Authors: Livingston-Rosanoff D; Daley-Bauer LP; Garcia A; McCormick AL; Huang J; Mocarski ES -
Activation of innate immunity is required for efficient nuclear reprogramming.
Cell Volume: 151 Page(s): 547 - 558
10/26/2012 Authors: Lee J; Sayed N; Hunter A; Au KF; Wong WH; Mocarski ES; Pera RR; Yakubov E; Cooke JP -
Mechanisms modulating immune clearance during human cytomegalovirus latency.
Proc Natl Acad Sci U S A Volume: 109 Page(s): 14291 - 14292
09/04/2012 Authors: Slobedman B; Mocarski ES -
Toll-Like Receptor 3 Activation Promotes Efficient Nuclear Reprogramming and Endothelial Differentiation
Volume: 111
08/03/2012 Authors: Sayed N; Lee J; Hunter A; Au KF; Wong W; Mocarski E; Pera RR; Cooke JP -
Viral and host control of cytomegalovirus maturation.
Trends Microbiol Volume: 20 Page(s): 392 - 401
08/01/2012 Authors: Tandon R; Mocarski ES -
Cytomegalovirus impairs antiviral CD8+ T cell immunity by recruiting inflammatory monocytes.
Immunity Volume: 37 Page(s): 122 - 133
07/27/2012 Authors: Daley-Bauer LP; Wynn GM; Mocarski ES -
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.
Cell Host Microbe Volume: 11 Page(s): 290 - 297
03/15/2012 Authors: Upton JW; Kaiser WJ; Mocarski ES -
Cytomegalovirus control of cell death pathways
From the Hallowed Halls of Herpesvirology: A Tribute to Bernard Roizman Page(s): 201 - 222
01/01/2012 Authors: McCormick AL; Mocarski ES -
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways.
Nat Rev Immunol Volume: 12 Page(s): 79 - 88
12/23/2011 Authors: Mocarski ES; Upton JW; Kaiser WJ -
Cytomegalovirus pUL96 is critical for the stability of pp150-associated nucleocapsids.
J Virol Volume: 85 Page(s): 7129 - 7141
07/01/2011 Authors: Tandon R; Mocarski ES -
Inhibition of 2',5'-oligoadenylate synthetase expression and function by the human cytomegalovirus ORF94 gene product.
J Virol Volume: 85 Page(s): 5696 - 5700
06/01/2011 Authors: Tan JCG; Avdic S; Cao JZ; Mocarski ES; White KL; Abendroth A; Slobedman B -
Identification and classification of acute cardiac rejection by intragraft transcriptional profiling.
Circulation Volume: 123 Page(s): 2236 - 2243
05/24/2011 Authors: Holweg CTJ; Potena L; Luikart H; Yu T; Berry GJ; Cooke JP; Valantine HA; Mocarski ES -
Cytomegalovirus UL103 controls virion and dense body egress.
J Virol Volume: 85 Page(s): 5125 - 5135
05/01/2011 Authors: Ahlqvist J; Mocarski E -
Human cytomegalovirus decreases constitutive transcription of MHC class II genes in mature Langerhans cells by reducing CIITA transcript levels.
Mol Immunol Volume: 48 Page(s): 1160 - 1167
05/01/2011 Authors: Lee AW; Wang N; Hornell TMC; Harding JJ; Deshpande C; Hertel L; Lacaille V; Pashine A; Macaubas C; Mocarski ES -
RIP3 mediates the embryonic lethality of caspase-8-deficient mice.
Nature Volume: 471 Page(s): 368 - 372
03/17/2011 Authors: Kaiser WJ; Upton JW; Long AB; Livingston-Rosanoff D; Daley-Bauer LP; Hakem R; Caspary T; Mocarski ES -
Virus inhibition of RIP3-dependent necrosis.
Cell Host Microbe Volume: 7 Page(s): 302 - 313
04/22/2010 Authors: Upton JW; Kaiser WJ; Mocarski ES -
Human cytomegalovirus exploits ESCRT machinery in the process of virion maturation.
J Virol Volume: 83 Page(s): 10797 - 10807
10/01/2009 Authors: Tandon R; AuCoin DP; Mocarski ES -
The spleen plays a central role in primary humoral alloimmunization to transfused mHEL red blood cells.
Transfusion Volume: 49 Page(s): 1678 - 1684
08/01/2009 Authors: Hendrickson JE; Saakadze N; Cadwell CM; Upton JW; Mocarski ES; Hillyer CD; Zimring JC -
Human herpesvirus replication and abnormal CD8+ T cell activation and low CD4+ T cell counts in antiretroviral-suppressed HIV-infected patients.
PLoS One Volume: 4 Page(s): e5277
01/01/2009 Authors: Jacobson MA; Ditmer DP; Sinclair E; Martin JN; Deeks SG; Hunt P; Mocarski ES; Shiboski C -
Frequent occult infection with cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis (Journal of Clinical Microbiology (2007) 45, 6 (1804-1810))
Journal of Clinical Microbiology Volume: 46 Page(s): 4121
12/01/2008 Authors: Potena L; Holweg CTJ; Vana ML; Bashyam L; Rajamani J; McCormick AL; Cooke JP; Valantine HA; Mocarski ES -
Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors.
J Immunol Volume: 181 Page(s): 6427 - 6434
11/01/2008 Authors: Kaiser WJ; Upton JW; Mocarski ES -
Control of cytoplasmic maturation events by cytomegalovirus tegument protein pp150.
J Virol Volume: 82 Page(s): 9433 - 9444
10/01/2008 Authors: Tandon R; Mocarski ES -
Repression of human cytomegalovirus major immediate early gene expression by the cellular transcription factor CCAAT displacement protein.
Virology Volume: 378 Page(s): 214 - 225
09/01/2008 Authors: Stern JL; Cao JZ; Xu J; Mocarski ES; Slobedman B -
Comparison of polymerase chain reaction of polymorphonuclear leukocytes and plasma identifies patients who control cytomegalovirus infection after hematopoietic cell transplantation.
Clin Infect Dis Volume: 47 Page(s): 535 - 539
08/15/2008 Authors: Vana ML; Formankova D; Cha S; Sharma A; Potena L; Brown JMY; Mocarski ES -
Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.
J Biol Chem Volume: 283 Page(s): 16966 - 16970
06/20/2008 Authors: Upton JW; Kaiser WJ; Mocarski ES -
HtrA2/Omi terminates cytomegalovirus infection and is controlled by the viral mitochondrial inhibitor of apoptosis (vMIA).
PLoS Pathog Volume: 4 Page(s): e1000063
05/09/2008 Authors: McCormick AL; Roback L; Mocarski ES -
Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus.
Transplantation Volume: 85 Page(s): 827 - 833
03/27/2008 Authors: Potena L; Fearon WF; Sydow K; Holweg C; Luikart H; Chin C; Weisshaar D; Mocarski ES; Lewis DB; Valantine HA -
RNA analysis by biosynthetic tagging using 4-thiouracil and uracil phosphoribosyltransferase.
Methods Mol Biol Volume: 419 Page(s): 135 - 146
01/01/2008 Authors: Zeiner GM; Cleary MD; Fouts AE; Meiring CD; Mocarski ES; Boothroyd JC -
Pathogen subversion of cell-intrinsic innate immunity (vol 8, pg 1179, 2007)
NATURE IMMUNOLOGY Volume: 9 Page(s): 105 - 105
01/01/2008 Authors: Roy CR; Mocarski ES -
Erratum: Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells (Nature Immunology (2007) vol. 8 (1372-1379))
Nature Immunology Volume: 9 Page(s): 105
01/01/2008 Authors: Roy CR; Mocarski ES -
Persistent and Latent Viral Infection
Encyclopedia of Virology Page(s): 108 - 116
01/01/2008 Authors: Mocarski ES; Grakoui A -
Human Cytomegalovirus: General Features
Encyclopedia of Virology Page(s): 474 - 485
01/01/2008 Authors: Mocarski ES; Pass RF -
Human Cytomegalovirus: General Features
Encyclopedia of Virology: Volume 1-5 Volume: 1-5 Page(s): V2-474-V2-485
01/01/2008 Authors: Mocarski ES; Pass RF -
Persistent and Latent Viral Infection
Encyclopedia of Virology: Volume 1-5 Volume: 1-5 Page(s): V4-108-V4-116
01/01/2008 Authors: Mocarski ES; Grakoui A -
Pathogen subversion of cell-intrinsic innate immunity.
Nat Immunol Volume: 8 Page(s): 1179 - 1187
11/01/2007 Authors: Roy CR; Mocarski ES -
Cyclosporine inhibits mouse cytomegalovirus infection via a cyclophilin-dependent pathway specifically in neural stem/progenitor cells.
J Virol Volume: 81 Page(s): 9013 - 9023
09/01/2007 Authors: Kawasaki H; Mocarski ES; Kosugi I; Tsutsui Y -
Frequent occult infection with Cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis.
J Clin Microbiol Volume: 45 Page(s): 1804 - 1810
06/01/2007 Authors: Potena L; Holweg CTJ; Vana ML; Bashyam L; Rajamani J; McCormick AL; Cooke JP; Valantine HA; Mocarski ES -
Interplay between systemic inflammation and markers of insulin resistance in cardiovascular prognosis after heart transplantation.
J Heart Lung Transplant Volume: 26 Page(s): 324 - 330
04/01/2007 Authors: Biadi O; Potena L; Fearon WF; Luikart HI; Yeung A; Ferrara R; Hunt SA; Mocarski ES; Valantine HA -
Changes in coronary arterial dimensions early after cardiac transplantation.
Transplantation Volume: 83 Page(s): 700 - 705
03/27/2007 Authors: Fearon WF; Potena L; Hirohata A; Sakurai R; Yamasaki M; Luikart H; Lee J; Vana ML; Cooke JP; Mocarski ES -
[Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome].
G Ital Cardiol (Rome) Volume: 8 Page(s): 73 - 82
02/01/2007 Authors: Potena L; Ferrara R; Mocarski ES; Lewis DB; Cooke JP; Grigioni F; Coccolo F; Magnani G; Fallani F; Magelli C -
Coronary allograft vasculopathy: Pathophysiological interaction between the immune system, infections and metabolic syndrome
Giornale Italiano di Cardiologia Volume: 8 Page(s): 73 - 82
02/01/2007 Authors: Potena L; Ferrara R; Mocarski ES; Lewis DB; Cooke JP; Grigioni F; Coccolo F; Magnani G; Fallani F; Magelli C -
Viral modulation of the host response to infection
HUMAN HERPESVIRUSES: BIOLOGY, THERAPY, AND IMMUNOPROPHYLAXIS Page(s): 324 - 337
01/01/2007 Authors: McCormick AL; Mocarski ES -
Viral and cell cycle-regulated kinases in cytomegalovirus-induced pseudomitosis and replication.
PLoS Pathog Volume: 3 Page(s): e6
01/01/2007 Authors: Hertel L; Chou S; Mocarski ES -
Comparative analysis of herpesvirus-common proteins
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis Page(s): 44 - 58
01/01/2007 Authors: Mocarski ES -
Betaherpes viral genes and their functions
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis Page(s): 204 - 230
01/01/2007 Authors: Mocarski ES -
CMV modulation of the host response to infection
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis Page(s): 324 - 338
01/01/2007 Authors: McCormick AL; Mocarski ES -
Human herpesviruses: Biology, therapy, and immunoprophylaxis
Page(s): 1 - 1410
01/01/2007 Authors: Arvin A; Campadelli-Fiume G; Mocarski E; Moore PS; Roizman B; Whitley R; Yamanishi K -
T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease.
Circulation Volume: 114 Page(s): 1608 - 1615
10/10/2006 Authors: Tu W; Potena L; Stepick-Biek P; Liu L; Dionis KY; Luikart H; Fearon WF; Holmes TH; Chin C; Cooke JP -
Human cytomegalovirus alters localization of MHC class II and dendrite morphology in mature Langerhans cells.
J Immunol Volume: 177 Page(s): 3960 - 3971
09/15/2006 Authors: Lee AW; Hertel L; Louie RK; Burster T; Lacaille V; Pashine A; Abate DA; Mocarski ES; Mellins ED -
Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model.
BMC Dev Biol Volume: 6 Page(s): 42
09/07/2006 Authors: Melnick M; Mocarski ES; Abichaker G; Huang J; Jaskoll T -
Updated guidelines on the management of cytomegalovirus reactivation in patients with chronic lymphocytic leukemia treated with alemtuzumab.
Clin Lymphoma Myeloma Volume: 7 Page(s): 125 - 130
09/01/2006 Authors: O'Brien SM; Keating MJ; Mocarski ES -
Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection.
Transplantation Volume: 82 Page(s): 398 - 405
08/15/2006 Authors: Potena L; Holweg CTJ; Chin C; Luikart H; Weisshaar D; Narasimhan B; Fearon WF; Lewis DB; Cooke JP; Mocarski ES -
Betaherpesvirus-conserved cytomegalovirus tegument protein ppUL32 (pp150) controls cytoplasmic events during virion maturation.
J Virol Volume: 80 Page(s): 8199 - 8210
08/01/2006 Authors: AuCoin DP; Smith GB; Meiering CD; Mocarski ES -
Increased sensitivity of two-step cytomegalovirus PCR analysis on peripheral blood leukocytes permits detailed analysis of reactivation and immune reconstitution
Volume: 12 Page(s): 30 - 30
02/01/2006 Authors: Vana ML; Formankova D; Cha S; Sharma A; Potena L; Brown JM; Mocarski ES -
Prevention of subclinical CMV infection reduces cardiac allograft disease progression by positively affecting coronary remodeling
JOURNAL OF HEART AND LUNG TRANSPLANTATION Volume: 25 Page(s): S138 - S139
02/01/2006 Authors: Potena L; Fearon W; Holweg C; Luikart H; Chin C; Cooke J; Lewis D; Mocarski E; Valantine H -
Inhibition of cardiac allograft vasculopathy by sirolimus and mycofenolate: Asymmetric dimethyl arginine as a potential therapeutic target
JOURNAL OF HEART AND LUNG TRANSPLANTATION Volume: 25 Page(s): S100 - S100
02/01/2006 Authors: Potena L; Fearon W; Sydow K; Holweg C; Luikart H; Mocarski E; Valantine H; Cooke J -
Cytomegalovirus MCK-2 controls mobilization and recruitment of myeloid progenitor cells to facilitate dissemination.
Blood Volume: 107 Page(s): 30 - 38
01/01/2006 Authors: Noda S; Aguirre SA; Bitmansour A; Brown JM; Sparer TE; Huang J; Mocarski ES -
Human cytomegalovirus alters localization of MHC class II and dendrite morphology in mature Langerhans cells.
Volume: 119 Page(s): S22 - S23
01/01/2006 Authors: Lee A; Hertel L; Louie R; Burster T; Lacaille V; Pashine A; Abate D; Mocarski E; Mellins E -
Contribution of GADD45 family members to cell death suppression by cellular Bcl-xL and cytomegalovirus vMIA.
J Virol Volume: 79 Page(s): 14923 - 14932
12/01/2005 Authors: Smith GB; Mocarski ES -
Pasteurella multocida bacteremia and tuboovarian abscess.
Obstet Gynecol Volume: 106 Page(s): 1220 - 1222
11/01/2005 Authors: Myckan KA; Booth CM; Mocarski E -
Mitochondrial cell death suppressors carried by human and murine cytomegalovirus confer resistance to proteasome inhibitor-induced apoptosis.
J Virol Volume: 79 Page(s): 12205 - 12217
10/01/2005 Authors: McCormick AL; Meiering CD; Smith GB; Mocarski ES -
Predicting coding potential from genome sequence: application to betaherpesviruses infecting rats and mice.
J Virol Volume: 79 Page(s): 7570 - 7596
06/01/2005 Authors: Brocchieri L; Kledal TN; Karlin S; Mocarski ES -
Cytomegalovirus infection is associated with acute left ventricular dysfunction in heart transplant recipients after antiviral prohylaxis.
Volume: 5 Page(s): 167 - 168
05/01/2005 Authors: Potena L; Holweg CTJ; Luikart HI; Levvis DB; Cooke JP; Mocarski ES; Valantine HA -
Subclinical cytomegalovirus infection modulates systemic inflammation and graft coronary remodeling one year after heart transplantation.
Volume: 5 Page(s): 382 - 382
05/01/2005 Authors: Potena L; Biadi O; Holweg C; Fearon W; Cooke J; Lewis D; Mocarski E; Valantine H -
Aggressive anti-cytomegalovirus prophylaxis and acute rejection in high risk patients: Beat the virus and prevent the rejection
JOURNAL OF HEART AND LUNG TRANSPLANTATION Volume: 24 Page(s): S117 - S118
02/01/2005 Authors: Potena L; Holweg C; Luikart H; Mocarski E; Lewis D; Cooke J; Chin C; Hunt S; Valantine H -
The carboxyl-terminal region of human cytomegalovirus IE1491aa contains an acidic domain that plays a regulatory role and a chromatin-tethering domain that is dispensable during viral replication.
J Virol Volume: 79 Page(s): 225 - 233
01/01/2005 Authors: Reinhardt J; Smith GB; Himmelheber CT; Azizkhan-Clifford J; Mocarski ES -
Cytomegalovirus-specific CD4 T-cell immunity is associated with protection from human cardiac allograft rejection and negative coronary-artery remodeling.
Volume: 115 Page(s): S277 - S277
01/01/2005 Authors: Tu W; Potena L; Stepick-Biek P; Liu L; Dionis KY; Bashyam L; Fearon W; Valantine TA; Mocarski ES; Lewis DB -
Global analysis of host cell gene expression late during cytomegalovirus infection reveals extensive dysregulation of cell cycle gene expression and induction of Pseudomitosis independent of US28 function.
J Virol Volume: 78 Page(s): 11988 - 12011
11/01/2004 Authors: Hertel L; Mocarski ES -
Systemic inflammation links impaired glucose metabolism to cardiac allograft vasculopathy development
Volume: 110 Page(s): 753 - 753
10/26/2004 Authors: Potena L; Biadi O; Fearon WB; Holweg CT; Luikart HI; Mocarski ES; Lewis DB; Valantine HA -
Expression of human CXCR2 in murine neutrophils as a model for assessing cytomegalovirus chemokine vCXCL-1 function in vivo.
J Interferon Cytokine Res Volume: 24 Page(s): 611 - 620
10/01/2004 Authors: Sparer TE; Gosling J; Schall TJ; Mocarski ES -
Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response.
J Virol Volume: 78 Page(s): 10995 - 11006
10/01/2004 Authors: Abate DA; Watanabe S; Mocarski ES -
Cytomegalovirus and heart transplant atherosclerosis: a likely guilt hidden by weak proofs.
Transplantation Volume: 78 Page(s): 631
08/27/2004 Authors: Potena L; Holweg C; Valantine HA; Mocarski ES -
Immune escape and exploitation strategies of cytomegaloviruses: impact on and imitation of the major histocompatibility system.
Cell Microbiol Volume: 6 Page(s): 707 - 717
08/01/2004 Authors: Mocarski ES -
Sex hormones and asymmetric dimethylarginine in transplant arteriosclerosis - Response
CIRCULATION Volume: 110 Page(s): E21 - E22
07/20/2004 Authors: Weis M; Cooke JP; Lin KY; Panchal SN; Gao SZ; Valantine HA; Kledal TN; Mocarski ES -
Impact of human cytomegalovirus latent infection on myeloid progenitor cell gene expression.
J Virol Volume: 78 Page(s): 4054 - 4062
04/01/2004 Authors: Slobedman B; Stern JL; Cunningham AL; Abendroth A; Abate DA; Mocarski ES -
Cytomegalovirus infectious burden is proportional to cardiac allograft vasculopathy in heart transplant recipients
Volume: 43 Page(s): 185A - 185A
03/03/2004 Authors: Potena L; Magelli C; Ortolani P; Fearon WF; Grigioni F; Magnani G; Coccolo F; Yeung AC; Luikart HI; Hunt SA -
Cytomegalovirus impairs endothelial nitric oxide synthase pathway: Role of oxidative stress and viral entry
Volume: 43 Page(s): 507A - 507A
03/03/2004 Authors: Iijima K; Noda S; Sydow K; Mocarski ES; Cooke JP -
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis.
Circulation Volume: 109 Page(s): 500 - 505
02/03/2004 Authors: Weis M; Kledal TN; Lin KY; Panchal SN; Gao SZ; Valantine HA; Mocarski ES; Cooke JP -
Asymptomatic cytomegalovirus activation leads to acute rejection in heart transplant recipients despite anti-viral prophylaxis.
Volume: 4 Page(s): 453 - 453
01/01/2004 Authors: Potena L; Holweg C; Luikart HI; Mocarski ES; Cooke JP; Lewis DB; Valantine HA -
Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegaloviruses.
Virology Volume: 316 Page(s): 221 - 233
11/25/2003 Authors: McCormick AL; Skaletskaya A; Barry PA; Mocarski ES; Goldmacher VS -
Cytomegalovirus, endothelial dysfunction and transplant arteriosclerosis
Volume: 108 Page(s): 546 - 546
10/28/2003 Authors: Weis M; Kledal TN; Lin KY; Panchal SN; Valantine HA; Mocarski ES; von Scheidt W; Meiser BM; Cooke JP -
Cytomegalovirus impairs the nitric oxide pathway. Role of ADMA in transplant arteriosclerosis
Volume: 24 Page(s): 214 - 214
08/01/2003 Authors: Weis M; Kledal TN; Lin KY; Panchal SN; Valantine HA; Mocarski E; Cooke JP -
Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.
Blood Volume: 102 Page(s): 421 - 428
07/15/2003 Authors: Arber C; BitMansour A; Sparer TE; Higgins JP; Mocarski ES; Weissman IL; Shizuru JA; Brown JMY -
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
J Virol Volume: 77 Page(s): 7563 - 7574
07/01/2003 Authors: Hertel L; Lacaille VG; Strobl H; Mellins ED; Mocarski ES -
NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.
J Exp Med Volume: 197 Page(s): 1245 - 1253
05/19/2003 Authors: Lodoen M; Ogasawara K; Hamerman JA; Arase H; Houchins JP; Mocarski ES; Lanier LL -
Pathologic features of uteri and leiomyomas following uterine artery embolization for leiomyomas.
Am J Surg Pathol Volume: 27 Page(s): 167 - 177
02/01/2003 Authors: Colgan TJ; Pron G; Mocarski EJM; Bennett JD; Asch MR; Common A -
Disruption of mitochondrial networks by the human cytomegalovirus UL37 gene product viral mitochondrion-localized inhibitor of apoptosis.
J Virol Volume: 77 Page(s): 631 - 641
01/01/2003 Authors: McCormick AL; Smith VL; Chow D; Mocarski ES -
NK cell-mediated lysis of autologous HCMV-infected skin fibroblasts is highly variable among NK cell clones and polyclonal NK cell lines.
Clin Immunol Volume: 105 Page(s): 126 - 140
11/01/2002 Authors: Carr WH; Little A-M; Mocarski E; Parham P -
Latent cytomegalovirus down-regulates major histocompatibility complex class II expression on myeloid progenitors.
Blood Volume: 100 Page(s): 2867 - 2873
10/15/2002 Authors: Slobedman B; Mocarski ES; Arvin AM; Mellins ED; Abendroth A -
Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion.
Trends Microbiol Volume: 10 Page(s): 332 - 339
07/01/2002 Authors: Mocarski ES -
Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors.
Science Volume: 296 Page(s): 1323 - 1326
05/17/2002 Authors: Arase H; Mocarski ES; Campbell AE; Hill AB; Lanier LL -
Modulation of MHC class II by human cytomegalovirus in dendritic cells
FASEB JOURNAL Volume: 16 Page(s): A1037 - A1037
03/22/2002 Authors: Lacaille VG; Hertel L; Strobl H; Mocarski ES; Mellins ED -
Virus self-improvement through inflammation: no pain, no gain.
Proc Natl Acad Sci U S A Volume: 99 Page(s): 3362 - 3364
03/19/2002 Authors: Mocarski ES -
The common lymphoid progenitor protects against lethal MCMV infection in a murine model of matched unrelated hematopoietic stem cell transplantation
BONE MARROW TRANSPLANTATION Volume: 29 Page(s): S67 - S67
03/01/2002 Authors: Arber C; BitMansour A; Higgins J; Mocarski ES; Shizuru JA; Brown JM -
Fatal attraction: cytomegalovirus-encoded chemokine homologs.
Curr Top Microbiol Immunol Volume: 269 Page(s): 235 - 256
01/01/2002 Authors: Saederup N; Mocarski ES -
The common lymphoid progenitor protects against lethal MCMV infection in a murine model of matched unrelated hematopoietic stem cell transplantation.
BLOOD Volume: 98 Page(s): 476A - 476A
11/16/2001 Authors: Arber C; BitMansour A; Mocarski ES; Shizuru JA; Brown JM -
Multicenter evaluation of PCR methods for detecting CMV DNA in blood donors.
Transfusion Volume: 41 Page(s): 1249 - 1257
10/01/2001 Authors: Roback JD; Hillyer CD; Drew WL; Laycock ME; Luka J; Mocarski ES; Slobedman B; Smith JW; Soderberg-Naucler C; Todd DS -
Murine cytomegalovirus CC chemokine homolog MCK-2 (m131-129) is a determinant of dissemination that increases inflammation at initial sites of infection.
J Virol Volume: 75 Page(s): 9966 - 9976
10/01/2001 Authors: Saederup N; Aguirre SA; Sparer TE; Bouley DM; Mocarski ES -
Requirement for uracil-DNA glycosylase during the transition to late-phase cytomegalovirus DNA replication.
J Virol Volume: 75 Page(s): 7592 - 7601
08/01/2001 Authors: Courcelle CT; Courcelle J; Prichard MN; Mocarski ES -
A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation.
Proc Natl Acad Sci U S A Volume: 98 Page(s): 7829 - 7834
07/03/2001 Authors: Skaletskaya A; Bartle LM; Chittenden T; McCormick AL; Mocarski ES; Goldmacher VS -
Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation.
Proc Natl Acad Sci U S A Volume: 98 Page(s): 1895 - 1900
02/13/2001 Authors: Wolf DG; Courcelle CT; Prichard MN; Mocarski ES -
Human cytomegalovirus latency-associated protein pORF94 is dispensable for productive and latent infection.
J Virol Volume: 74 Page(s): 9333 - 9337
10/01/2000 Authors: White KL; Slobedman B; Mocarski ES -
Humoral immune response to proteins of human cytomegalovirus latency-associated transcripts.
Biol Blood Marrow Transplant Volume: 6 Page(s): 100 - 108
01/01/2000 Authors: Landini MP; Lazzarotto T; Xu J; Geballe AP; Mocarski ES -
Cytomegalovirus cell tropism, replication, and gene transfer in brain.
J Neurosci Volume: 19 Page(s): 10948 - 10965
12/15/1999 Authors: van Den Pol AN; Mocarski E; Saederup N; Vieira J; Meier TJ -
Comparison of 7 PCR assays for detection of cytomegalovirus (CMV) DNA in pbmcs of blood donors: Results of a blinded multicenter study.
BLOOD Volume: 94 Page(s): 246A - 246A
11/15/1999 Authors: Roback JD; Hillyer CD; Drew WL; Luka J; Mocarski ES; Soderberg-Naucler C; Woxenius S; Busch MP -
A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.
Proc Natl Acad Sci U S A Volume: 96 Page(s): 12536 - 12541
10/26/1999 Authors: Goldmacher VS; Bartle LM; Skaletskaya A; Dionne CA; Kedersha NL; Vater CA; Han JW; Lutz RJ; Watanabe S; Cahir McFarland ED -
Cytomegalovirus-encoded beta chemokine promotes monocyte-associated viremia in the host.
Proc Natl Acad Sci U S A Volume: 96 Page(s): 10881 - 10886
09/14/1999 Authors: Saederup N; Lin YC; Dairaghi DJ; Schall TJ; Mocarski ES -
Cytomegalovirus encodes a potent alpha chemokine.
Proc Natl Acad Sci U S A Volume: 96 Page(s): 9839 - 9844
08/17/1999 Authors: Penfold ME; Dairaghi DJ; Duke GM; Saederup N; Mocarski ES; Kemble GW; Schall TJ -
Tetracycline-mediated regulation of gene expression within the human cytomegalovirus genome.
Virology Volume: 258 Page(s): 295 - 303
06/05/1999 Authors: McVoy MA; Mocarski ES -
Quantitative analysis of latent human cytomegalovirus.
J Virol Volume: 73 Page(s): 4806 - 4812
06/01/1999 Authors: Slobedman B; Mocarski ES -
Analysis of host viral interactions in CMV infection using DNA microarrays.
TRANSPLANTATION Volume: 67 Page(s): S611 - S611
05/15/1999 Authors: Barry CT; Watanabe S; Mocarski ES; Brown PO -
Peripheral blood CD14(+) cells from healthy subjects carry a circular conformation of latent cytomegalovirus genome.
Blood Volume: 93 Page(s): 394 - 398
01/01/1999 Authors: Bolovan-Fritts CA; Mocarski ES; Wiedeman JA -
Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: The role of endogenous class I major histocompatibility complex and a viral class I homolog (vol 187, pg 1681, 1998)
JOURNAL OF EXPERIMENTAL MEDICINE Volume: 188 Page(s): 615 - 615
08/03/1998 Authors: Leong CC; Chapman TL; Bjorkman PJ; Formankova D; Mocarski ES; Phillips JH; Lanier LL -
Modulation of natural killer cell cytotoxicity in human cytomegalovirus infection: the role of endogenous class I major histocompatibility complex and a viral class I homolog.
J Exp Med Volume: 187 Page(s): 1681 - 1687
05/18/1998 Authors: Leong CC; Chapman TL; Bjorkman PJ; Formankova D; Mocarski ES; Phillips JH; Lanier LL -
Enhancement of obliterative airway disease in rat tracheal allografts infected with recombinant rat cytomegalovirus.
J Heart Lung Transplant Volume: 17 Page(s): 439 - 451
05/01/1998 Authors: Reichenspurner H; Soni V; Nitschke M; Berry GJ; Brazelton T; Shorthouse R; Huang X; Boname J; Girgis R; Raitz BA -
Formation of cytomegalovirus DNA replication compartments defined by localization of viral proteins and DNA synthesis (vol 239, pg 46, 1997)
VIROLOGY Volume: 243 Page(s): 497 - 497
04/10/1998 Authors: Penfold MET; Mocarski ES -
Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells.
Proc Natl Acad Sci U S A Volume: 95 Page(s): 3937 - 3942
03/31/1998 Authors: Hahn G; Jores R; Mocarski ES -
Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.
J Virol Volume: 72 Page(s): 366 - 379
01/01/1998 Authors: Greaves RF; Mocarski ES -
Sequences within the herpesvirus-conserved pac1 and pac2 motifs are required for cleavage and packaging of the murine cytomegalovirus genome.
J Virol Volume: 72 Page(s): 48 - 56
01/01/1998 Authors: McVoy MA; Nixon DE; Adler SP; Mocarski ES -
Reassessing the organization of the UL42-UL43 region of the human cytomegalovirus strain AD169 genome.
Virology Volume: 239 Page(s): 169 - 175
12/08/1997 Authors: Mocarski ES; Prichard MN; Tan CS; Brown JM -
Formation of cytomegalovirus DNA replication compartments defined by localization of viral proteins and DNA synthesis.
Virology Volume: 239 Page(s): 46 - 61
12/08/1997 Authors: Penfold ME; Mocarski ES -
The location and sequence composition of the murine cytomegalovirus replicator (oriLyt).
Virology Volume: 230 Page(s): 350 - 360
04/14/1997 Authors: Masse MJ; Messerle M; Mocarski ES -
The synthesis and immunogenicity of varicella-zoster virus glycoprotein E and immediate-early protein (IE62) expressed in recombinant herpes simplex virus-1.
Antiviral Res Volume: 33 Page(s): 187 - 200
02/01/1997 Authors: Lowry PW; Koropchak CM; Choi CY; Mocarski ES; Kern ER; Kinchington PR; Arvin AM -
Human cytomegalovirus infection inhibits G1/S transition.
J Virol Volume: 71 Page(s): 1629 - 1634
02/01/1997 Authors: Dittmer D; Mocarski ES -
Propagating Kaposi's sarcoma-associated herpesvirus.
N Engl J Med Volume: 336 Page(s): 214 - 215
01/16/1997 Authors: Mocarski ES -
A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation.
Proc Natl Acad Sci U S A Volume: 93 Page(s): 11321 - 11326
10/15/1996 Authors: Mocarski ES; Kemble GW; Lyle JM; Greaves RF -
Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals.
Proc Natl Acad Sci U S A Volume: 93 Page(s): 11137 - 11142
10/01/1996 Authors: Kondo K; Xu J; Mocarski ES -
Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication.
J Virol Volume: 70 Page(s): 3018 - 3025
05/01/1996 Authors: Prichard MN; Duke GM; Mocarski ES -
Recombinant cytomegaloviruses for study of replication and pathogenesis.
Intervirology Volume: 39 Page(s): 320 - 330
01/01/1996 Authors: Mocarski ES; Kemble GW -
Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.
J Virol Volume: 70 Page(s): 78 - 83
01/01/1996 Authors: Cha TA; Tom E; Kemble GW; Duke GM; Mocarski ES; Spaete RR -
A subset of patients with the chronic fatigue syndrome is a primary cardiomyopathy associated with persistent cytomegalovirus infection ALT lerner
Journal of Investigative Medicine Volume: 44
01/01/1996 Authors: Zervos M; Dworkin HJ; Chang C; Goldstein J; Mocarski E -
Cytomegalovirus latency and latency-specific transcription in hematopoietic progenitors.
Scandinavian journal of infectious diseases. Supplementum Volume: 99 Page(s): 63 - 67
12/01/1995 Authors: Kondo K; Mocarski ES -
Selectable insertion and deletion mutagenesis of the human cytomegalovirus genome using the Escherichia coli guanosine phosphoribosyl transferase (gpt) gene.
J Gen Virol Volume: 76 ( Pt 9) Page(s): 2151 - 2160
09/01/1995 Authors: Greaves RF; Brown JM; Vieira J; Mocarski ES -
Dramatic interstrain differences in the replication of human cytomegalovirus in SCID-hu mice.
J Infect Dis Volume: 171 Page(s): 1599 - 1603
06/01/1995 Authors: Brown JM; Kaneshima H; Mocarski ES -
Murine cytomegalovirus IE2, an activator of gene expression, is dispensable for growth and latency in mice.
Virology Volume: 209 Page(s): 236 - 241
05/10/1995 Authors: Cardin RD; Abenes GB; Stoddart CA; Mocarski ES -
Cytomegalovirus latency and latency-specific transcription in hematopoietic progenitors.
Scand J Infect Dis Suppl Volume: 99 Page(s): 63 - 67
01/01/1995 Authors: Kondo K; Mocarski ES -
Human cytomegalovirus latent infection of granulocyte-macrophage progenitors.
Proc Natl Acad Sci U S A Volume: 91 Page(s): 11879 - 11883
12/06/1994 Authors: Kondo K; Kaneshima H; Mocarski ES -
Structure and function of the murine cytomegalovirus sgg1 gene: a determinant of viral growth in salivary gland acinar cells.
J Virol Volume: 68 Page(s): 7717 - 7727
12/01/1994 Authors: Lagenaur LA; Manning WC; Vieira J; Martens CL; Mocarski ES -
Peripheral blood mononuclear phagocytes mediate dissemination of murine cytomegalovirus.
J Virol Volume: 68 Page(s): 6243 - 6253
10/01/1994 Authors: Stoddart CA; Cardin RD; Boname JM; Manning WC; Abenes GB; Mocarski ES -
Human cytomegalovirus late protein encoded by ie2: a trans-activator as well as a repressor of gene expression.
J Gen Virol Volume: 75 ( Pt 9) Page(s): 2337 - 2348
09/01/1994 Authors: Jenkins DE; Martens CL; Mocarski ES -
Genes in the HindIII J fragment of the murine cytomegalovirus genome are dispensable for growth in cultured cells: insertion mutagenesis with a lacZ/gpt cassette.
J Virol Volume: 68 Page(s): 4837 - 4846
08/01/1994 Authors: Vieira J; Farrell HE; Rawlinson WD; Mocarski ES -
GENETIC-DETERMINANTS OF PERSISTENT REPLICATION OF HUMAN CYTOMEGALOVIRUS IN HUMAN FETAL TISSUE
CLINICAL RESEARCH Volume: 42 Page(s): A299 - A299
04/01/1994 Authors: BROWN JM; MOCARSKI ES -
Molecular evolution of herpesviruses: genomic and protein sequence comparisons.
J Virol Volume: 68 Page(s): 1886 - 1902
03/01/1994 Authors: Karlin S; Mocarski ES; Schachtel GA -
Altering central nervous system physiology with a defective herpes simplex virus vector expressing the glucose transporter gene.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 3655 - 3659
04/15/1993 Authors: Ho DY; Mocarski ES; Sapolsky RM -
HUMAN CYTOMEGALOVIRUS-INFECTION IN THE SCID-HU MOUSE
JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 67 - 67
03/29/1993 Authors: KANESHIMA H; BONYHADI M; SALIMI S; MCCUNE JM; MOCARSKI ES -
Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 104 - 108
01/01/1993 Authors: Mocarski ES; Bonyhadi M; Salimi S; McCune JM; Kaneshima H -
Recombination in vitro between herpes simplex virus type 1 a sequences.
Proc Natl Acad Sci U S A Volume: 89 Page(s): 10950 - 10954
11/15/1992 Authors: Bruckner RC; Dutch RE; Zemelman BV; Mocarski ES; Lehman IR -
Infection of hematopoietic progenitor cells by human cytomegalovirus.
Blood Volume: 80 Page(s): 170 - 178
07/01/1992 Authors: Maciejewski JP; Bruening EE; Donahue RE; Mocarski ES; Young NS; St Jeor SC -
Human cytomegalovirus origin of DNA replication (oriLyt) resides within a highly complex repetitive region.
Proc Natl Acad Sci U S A Volume: 89 Page(s): 5246 - 5250
06/15/1992 Authors: Masse MJ; Karlin S; Schachtel GA; Mocarski ES -
Cytomegalovirus determinant of replication in salivary glands.
J Virol Volume: 66 Page(s): 3794 - 3802
06/01/1992 Authors: Manning WC; Stoddart CA; Lagenaur LA; Abenes GB; Mocarski ES -
Neutralizing epitopes on herpes simplex virus-1-expressed rotavirus VP7 are dependent on coexpression of other rotavirus proteins.
Virology Volume: 187 Page(s): 18 - 32
03/01/1992 Authors: Dormitzer PR; Ho DY; Mackow ER; Mocarski ES; Greenberg HB -
Transactivation of the cytomegalovirus ICP36 gene promoter requires the alpha gene product TRS1 in addition to IE1 and IE2.
J Virol Volume: 66 Page(s): 1050 - 1058
02/01/1992 Authors: Stasiak PC; Mocarski ES -
Herpes simplex virus type 1 recombination: role of DNA replication and viral a sequences.
J Virol Volume: 66 Page(s): 277 - 285
01/01/1992 Authors: Dutch RE; Bruckner RC; Mocarski ES; Lehman IR -
Evidence for selective evolution in codon usage in conserved amino acid segments of human alphaherpesvirus proteins.
J Mol Evol Volume: 33 Page(s): 483 - 494
12/01/1991 Authors: Schachtel GA; Bucher P; Mocarski ES; Blaisdell BE; Karlin S -
Initial events involved in cytomegalovirus-cell interactions.
Transplant Proc Volume: 23 Page(s): 43 - 47
06/01/1991 Authors: Mocarski ES -
INITIAL EVENTS INVOLVED IN CYTOMEGALOVIRUS CELL-INTERACTIONS
Volume: 23 Page(s): 43 - 47
06/01/1991 Authors: MOCARSKI ES -
Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start site.
J Virol Volume: 65 Page(s): 887 - 896
02/01/1991 Authors: Cherrington JM; Khoury EL; Mocarski ES -
THE PRODUCTS OF HUMAN CYTOMEGALOVIRUS GENES UL1-UL7, INCLUDING GP48, ARE DISPENSABLE FOR GROWTH IN CELL-CULTURE
Volume: 978 Page(s): 57 - 60
01/01/1991 Authors: RIPALTI A; MOCARSKI ES -
TRANSACTIVATION OF A CYTOMEGALOVIRUS GAMMA-GENE PROMOTER REQUIRES TRS1, A MEMBER OF THE US22 FAMILY
Volume: 978 Page(s): 63 - 79
01/01/1991 Authors: STASIAK PC; MOCARSKI ES -
Initial events involved in cytomegalovirus-cell interactions
Volume: 23 Page(s): 43 - 47
01/01/1991 Authors: Mocarski ES -
Molecular genetic analysis of cytomegalovirus gene regulation in growth, persistence and latency.
Curr Top Microbiol Immunol Volume: 154 Page(s): 47 - 74
01/01/1990 Authors: Mocarski ES; Abenes GB; Manning WC; Sambucetti LC; Cherrington JM -
NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation.
EMBO J Volume: 8 Page(s): 4251 - 4258
12/20/1989 Authors: Sambucetti LC; Cherrington JM; Wilkinson GW; Mocarski ES -
A host cell protein binds to a highly conserved sequence element (pac-2) within the cytomegalovirus a sequence.
J Virol Volume: 63 Page(s): 4715 - 4728
11/01/1989 Authors: Kemble GW; Mocarski ES -
Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse.
Proc Natl Acad Sci U S A Volume: 86 Page(s): 7596 - 7600
10/01/1989 Authors: Ho DY; Mocarski ES -
Cytomegalovirus enhances lysis of HIV-infected T lymphoblasts.
Int J Cancer Volume: 44 Page(s): 124 - 130
07/15/1989 Authors: Casareale D; Fiala M; Chang CM; Cone LA; Mocarski ES -
Identification and preliminary use of recombinant lambda gt11 fusion proteins in human cytomegalovirus diagnosis.
J Gen Virol Volume: 70 ( Pt 5) Page(s): 1247 - 1251
05/01/1989 Authors: Ripalti A; Landini MP; Mocarski ES; La Placa M -
Herpes simplex virus 1 helicase-primase: a complex of three herpes-encoded gene products.
Proc Natl Acad Sci U S A Volume: 86 Page(s): 2186 - 2189
04/01/1989 Authors: Crute JJ; Tsurumi T; Zhu LA; Weller SK; Olivo PD; Challberg MD; Mocarski ES; Lehman IR -
Regulation of cytomegalovirus late-gene expression: differential use of three start sites in the transcriptional activation of ICP36 gene expression.
J Virol Volume: 63 Page(s): 1783 - 1791
04/01/1989 Authors: Leach FS; Mocarski ES -
Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.
J Virol Volume: 63 Page(s): 1435 - 1440
03/01/1989 Authors: Cherrington JM; Mocarski ES -
A method to identify distinctive charge configurations in protein sequences, with application to human herpesvirus polypeptides.
J Mol Biol Volume: 205 Page(s): 165 - 177
01/05/1989 Authors: Karlin S; Blaisdell BE; Mocarski ES; Brendel V -
Biology and replication of cytomegalovirus.
Transfus Med Rev Volume: 2 Page(s): 229 - 234
12/01/1988 Authors: Mocarski ES -
Insertional mutagenesis of the murine cytomegalovirus genome: one prominent alpha gene (ie2) is dispensable for growth.
Virology Volume: 167 Page(s): 477 - 484
12/01/1988 Authors: Manning WC; Mocarski ES -
Beta-galactosidase as a marker in the peripheral and neural tissues of the herpes simplex virus-infected mouse.
Virology Volume: 167 Page(s): 279 - 283
11/01/1988 Authors: Ho DY; Mocarski ES -
The cleavage recognition signal is contained within sequences surrounding an a-a junction in herpes simplex virus DNA.
Virology Volume: 167 Page(s): 25 - 30
11/01/1988 Authors: Nasseri M; Mocarski ES -
Human cytomegalovirus ICP22, the product of the HWLF1 reading frame, is an early nuclear protein that is released from cells.
J Gen Virol Volume: 69 ( Pt 10) Page(s): 2613 - 2621
10/01/1988 Authors: Mocarski ES; Pereira L; McCormick AL -
Translational control of cytomegalovirus gene expression is mediated by upstream AUG codons.
J Virol Volume: 62 Page(s): 3334 - 3340
09/01/1988 Authors: Geballe AP; Mocarski ES -
VIRAL VECTORS - A MEETING REVIEW
GENES & DEVELOPMENT Volume: 2 Page(s): 926 - 928
08/01/1988 Authors: MOCARSKI E -
A DNA helicase induced by herpes simplex virus type 1.
Nucleic Acids Res Volume: 16 Page(s): 6585 - 6596
07/25/1988 Authors: Crute JJ; Mocarski ES; Lehman IR -
A DNA HELICASE INDUCED BY HERPES-SIMPLEX VIRUS TYPE-1
NUCLEIC ACIDS RESEARCH Volume: 16 Page(s): 6585 - 6596
07/25/1988 Authors: CRUTE JJ; MOCARSKI ES; LEHMAN IR -
A DNA helicase induced by herpes simplex virus type 1
Nucleic Acids Research Volume: 16 Page(s): 6585 - 6596
07/25/1988 Authors: Crute JJ; Mocarski ES; Lehman IR -
-galactosidase as a marker in the peripheral and neural tissues of the herpes simplex virus-infected mouse
Virology Volume: 167 Page(s): 279 - 283
01/01/1988 Authors: Ho DY; Mocarski ES -
A cytomegalovirus protein with properties of herpes simplex virus ICP8: partial purification of the polypeptide and map position of the gene.
J Virol Volume: 61 Page(s): 3143 - 3151
10/01/1987 Authors: Kemble GW; McCormick AL; Pereira L; Mocarski ES -
Insertion and deletion mutagenesis of the human cytomegalovirus genome.
Proc Natl Acad Sci U S A Volume: 84 Page(s): 7213 - 7217
10/01/1987 Authors: Spaete RR; Mocarski ES -
Structure and variability of the a sequence in the genome of human cytomegalovirus (Towne strain).
J Gen Virol Volume: 68 ( Pt 8) Page(s): 2223 - 2230
08/01/1987 Authors: Mocarski ES; Liu AC; Spaete RR -
A cis-acting element within the 5' leader of a cytomegalovirus beta transcript determines kinetic class.
Cell Volume: 46 Page(s): 865 - 872
09/12/1986 Authors: Geballe AP; Spaete RR; Mocarski ES -
A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.
Proc Natl Acad Sci U S A Volume: 83 Page(s): 6322 - 6326
09/01/1986 Authors: Elias P; O'Donnell ME; Mocarski ES; Lehman IR -
Regulation of cytomegalovirus late gene expression: gamma genes are controlled by posttranscriptional events.
J Virol Volume: 57 Page(s): 864 - 874
03/01/1986 Authors: Geballe AP; Leach FS; Mocarski ES -
Cytomegalovirus viremia increases with progressive immune deficiency in patients infected with HTLV-III.
AIDS Res Volume: 2 Page(s): 175 - 181
01/01/1986 Authors: Fiala M; Cone LA; Chang CM; Mocarski ES -
Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts.
J Virol Volume: 56 Page(s): 135 - 143
10/01/1985 Authors: Spaete RR; Mocarski ES -
Nucleotide sequence and structural features of a novel US-a junction present in a defective herpes simplex virus genome.
J Virol Volume: 55 Page(s): 140 - 146
07/01/1985 Authors: Mocarski ES; Deiss LP; Frenkel N -
The alpha sequence of the cytomegalovirus genome functions as a cleavage/packaging signal for herpes simplex virus defective genomes.
J Virol Volume: 54 Page(s): 817 - 824
06/01/1985 Authors: Spaete RR; Mocarski ES -
Precise localization of genes on large animal virus genomes: use of lambda gt11 and monoclonal antibodies to map the gene for a cytomegalovirus protein family.
Proc Natl Acad Sci U S A Volume: 82 Page(s): 1266 - 1270
02/01/1985 Authors: Mocarski ES; Pereira L; Michael N -
The a sequence of the cytomegalovirus genome functions as a cleavage/packaging signal for herpes simplex virus defective genomes
Journal of Virology Volume: 54 Page(s): 817 - 824
01/01/1985 Authors: Spaete RR; Mocarski ES -
Multiple infections by cytomegalovirus in patients with acquired immunodeficiency syndrome: documentation by Southern blot hybridization.
J Infect Dis Volume: 150 Page(s): 952 - 953
12/01/1984 Authors: Drew WL; Sweet ES; Miner RC; Mocarski ES -
INFECTION OF HUMAN-SKIN MICROVASCULAR ENDOTHELIAL-CELLS BY CYTOMEGALOVIRUS
CLINICAL RESEARCH Volume: 32 Page(s): A593 - A593
01/01/1984 Authors: KARASEK M; BENSCH K; MOCARSKI E -
Presence of prostaglandin F receptors coupled to adenylate cyclase in cerebrovascular muscle culture
Stroke Volume: 14
01/01/1983 Authors: Mocarski E; Spatz M; Wroblewska B -
PRESENCE OF PROSTAGLANDIN-F RECEPTORS COUPLED TO ADENYLATE-CYCLASE IN CEREBROVASCULAR MUSCLE CULTURE
STROKE Volume: 14 Page(s): 131 - 131
01/01/1983 Authors: MOCARSKI E; SPATZ M; WROBLEWSKA B; MERKEL N; BEMBRY J -
Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA.
Cell Volume: 31 Page(s): 89 - 97
11/01/1982 Authors: Mocarski ES; Roizman B -
Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication.
Proc Natl Acad Sci U S A Volume: 79 Page(s): 5626 - 5630
09/01/1982 Authors: Mocarski ES; Roizman B -
Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication
Proceedings of the National Academy of Sciences of the United States of America Volume: 79 Page(s): 5626 - 5630
01/01/1982 Authors: Mocarski ES; Roizman B -
Site-specific inversion sequence of the herpes simplex virus genome: domain and structural features.
Proc Natl Acad Sci U S A Volume: 78 Page(s): 7047 - 7051
11/01/1981 Authors: Mocarski ES; Roizman B -
Site specific inversion sequence of the herpes simplex virus genome: Domain and structural features
Proceedings of the National Academy of Sciences of the United States of America Volume: 78 Page(s): 7047 - 7051
01/01/1981 Authors: Mocarski ES; Roizman B -
Molecular engineering of the herpes simplex virus genome: insertion of a second L-S junction into the genome causes additional genome inversions.
Cell Volume: 22 Page(s): 243 - 255
11/01/1980 Authors: Mocarski ES; Post LE; Roizman B -
Cloning of reiterated and nonreiterated herpes simplex virus 1 sequences as BamHI fragments.
Proc Natl Acad Sci U S A Volume: 77 Page(s): 4201 - 4205
07/01/1980 Authors: Post LE; Conley AJ; Mocarski ES; Roizman B -
MOLECULAR ENGINEERING OF THE HERPES-SIMPLEX VIRUS GENOME - INSERTION OF A SECOND L-S JUNCTION INTO THE GENOME CAUSES ADDITIONAL GENOME INVERSIONS
CELL Volume: 22 Page(s): 243 - 255
01/01/1980 Authors: MOCARSKI ES; POST LE; ROIZMAN B -
Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions
Cell Volume: 22 Page(s): 243 - 255
01/01/1980 Authors: Mocarski ES; Post LE; Roizman B -
Persistence of the cytomegalovirus genome in human cells.
J Virol Volume: 31 Page(s): 761 - 775
09/01/1979 Authors: Mocarski ES; Stinski MF -
DNA of human cytomegalovirus: size heterogeneity and defectiveness resulting from serial undiluted passage.
J Virol Volume: 31 Page(s): 231 - 239
07/01/1979 Authors: Stinski MF; Mocarski ES; Thomsen DR -
Membrane glycoproteins and antigens induced by human cytomegalovirus.
J Gen Virol Volume: 43 Page(s): 119 - 129
04/01/1979 Authors: Stinski MF; Mocarski ES; Thomsen DR; Urbanowski ML -
MEMBRANE-GLYCOPROTEINS AND ANTIGENS INDUCED BY HUMAN CYTOMEGALO-VIRUS
JOURNAL OF GENERAL VIROLOGY Volume: 43 Page(s): 119 - 129
01/01/1979 Authors: STINSKI MF; MOCARSKI ES; THOMSEN DR; URBANOWSKI ML